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Jacobs Built Multi-Product Cell Culture Facility in Ireland Wins International Award

Infra News - Published on Sat, 27 Jun 2020

Image Source: Jacobs Cruiserath Biologics
Jacobs provided architecture, engineering, construction management and turnover services for a world class biopharmaceutical manufacturing facility, Cruiserath Biologics based in Dublin in Ireland, which, has won the Project Execution category at the International Society for Pharmaceutical Engineering 2020 Facility of the Year Awards. The award recognizes innovation in facilities serving the regulated healthcare industry. The factory, optimized for rapid product changeover and future use as a multi-product facility, will support Bristol Myers Squibb in meeting growing global demand for its medicines.

In 2015, biopharmaceutical manufacturer Bristol Myers Squibb engaged Jacobs to reimagine its existing active pharmaceutical ingredients plant in Dublin, Ireland, to enable large-scale production of its vital immuno-oncology medicines. Representing an innovative approach to fighting cancer, immuno-oncology seeks to harness the body's own immune system to combat tumor cells. Jacobs was tasked with creating a facility of the future for the USD 1 billion Multi-Product Cell Culture facility. At the time, the project represented the largest pharmaceutical project being undertaken in Europe, with more than 2,200 people on site at peak. The project's fast-tracked 26-month delivery commanded collaboration from Jacobs' global network of expertise across Ireland, the United States and India, working around the clock to meet the ambitious schedule.

The complexity, scale and speed of execution required game-changing project delivery. A detailed and robust project execution plan was developed to address challenges, monitor progress and ensure project success. The facility was delivered within budget, applying state–of–the–art project delivery techniques and tools, and achieving an impressive safety record during the 6.5 million hours worked. The facility was also awarded LEED Silver certification for its sustainability performance in respect of design, construction and operation.

The facility met the design intent to be a flexible, multi-product manufacturing operation able to produce biopharmaceuticals for human therapeutic use. The project repurposed an existing site to design and construct a new manufacturing facility, global laboratory, offices, cafeteria, utility and warehouse buildings as one functional campus. The facility is now in commercial operation, having recently received regulatory approval from both the FDA and the European Medicines Authority.

Supply Partners and Key Participants:
Manufacturer/Owner Name - Bristol Myers Squibb
Engineer/Architect (A&E) - Jacobs
Construction Manager - Jacobs
Main/General Contractor - Jacobs
Piping Subcontractors - Jones Engineering Mercury Engineering & Leo Lynch & Co
HVAC Subcontractor - Rockwell Engineering
Automation and Control Supplier - Sirus
Major Equipment Suppliers/Contractors – Techniserv, IPEC, PALL Corporation, Steris Ltd, Millipore, FlowTech, Radley Engineering Ltd, BCD Engineering

Source :

Posted By : Yogender Pancholi on Sat, 27 Jun 2020
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